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Updated: Jan 17, 2026

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy
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Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy

Published on: June 25, 2013

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Mrx6 结合了 Lon 蛋白酶 Pim1 N-终端域,从而赋予选择性基质特异性,并调节 mtDNA 拷贝数

Simon Schrott1, Ilaria Marafelli1, Charlotte Gerle1

  • 1Faculty of Biology, Ludwig-Maximilians-Universität München, Großhaderner Straße 2-4, Planegg-Martinsried 82152, Germany.

Nucleic acids research
|January 14, 2026
PubMed
概括

线粒体蛋白Mrx6通过与Lon蛋白酶Pim1.1相互作用,调节线粒体DNA (mtDNA) 拷贝数. 丢失Mrx6或它的伴侣会增加mtDNA拷贝数,影响细胞功能.

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Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells

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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

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相关概念视频

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Abnormal Proliferation

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Mismatch Repair

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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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