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线粒体向的HDAP2保护了视网膜质细胞,并增加了DBA/2J小鼠的压力耐受性

Margaret A MacNeil1, Widnie Mentor1, Alexander Birk1,2

  • 1Department of Biology, York College of the City University of New York, Jamaica, NY, United States.

Investigative ophthalmology & visual science
|January 14, 2026
PubMed
概括

一种新型的,HDAP2,显著地保护了视网膜细胞 (RGC) 和视神经轴突免受青光眼引起的小鼠损伤. 这为眼提供了潜在的新疗法,即使在目前治疗方法耐药的情况下也是如此.

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Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...