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在扫描的质子束中使用水热度计测试对光束质量校正因子的实验性确定

Lies Verpoest¹, Séverine Rossomme², Kevin Souris³

¹Institut de Recherche Expérimentale et Clinique-Molecular Imaging Radiotherapy and Oncology (MIRO), UCLouvain, av Hippocrate 55, Brussels, 1200, BELGIUM.

Physics in medicine and biology

|January 14, 2026

概括

这项研究使用水热量计测量了质量校正因子 (kQ) 在质子疗法. 结果验证了当前的剂量测量协议,并为扫描的质子束提供了关键数据.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
剂量测量方法剂量测量方法

背景情况:

准确的剂量测量对于有效的质子疗法至关重要.
波束质量校正因子 (kQ) 对于精确的剂量传递至关重要.
对扫描的质子束的实验数据是有限的.

研究的目的:

在单层扫描的质子束中实验性地确定kQ因子.
用三种常见的电离室类型来比较测量结果.
为了验证现有的剂量测量协议,并提供基准数据.

主要方法:

用水热量计测量吸收剂量与水的比例.
在两个中心用临床质子束 (150-226 MeV) 进行测量.
研究了三个电离室模型 (FC65-G,PPC05,PPC40).

主要成果:

测量的kQ因子通常与TRS-398 Rev.一致. 1 (2024) 的建议.
FC65-G室的结果与以前的水热量计数据保持一致.
PPC40室显示<0.5%的偏差与TRS-398修订版. 1; PPC05室显示<1.4%的偏差.

结论:

这项研究为扫描的质子束提供了新的实验kQ因子.
这些发现支持当前剂量计方案的有效性 (TRS-398 Rev. 1). 1). 一个 1). 一个 1).
数据作为蒙特卡洛模拟和未来剂量测量研究的基准.

关键词:

波束质量校正因子波束质量校正因子电离室是电离室中的一个.质子束是一种质子束.水热量计是用水的热量计.

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