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ADAM10和ADAM17通过直接蛋白质溶解或间接上调蛋白质合成,以不同的方式调节诱导的肺ACE释放

Yan Yu1, Aaron Babendreyer1, Alessa Pabst1

  • 1Institute of Molecular Pharmacology, University Hospital RWTH Aachen, Aachen, Germany.

Biochimica et biophysica acta. Molecular cell research
|January 14, 2026
PubMed
概括

溶解性血管激素转化酶 (ACE) 的释放主要由ADAM10介导,而ADAM17则扮演间接的角色. 这一过程受到各种因素的影响,影响心血管健康.

关键词:
ангиотензин转化酶-转化酶-转化酶氧气过低是因为缺氧.炎症 炎症是一种炎症.肺内皮是肺的内皮.金属蛋白质酶 (metalloproteinase) 的使用方法精密切割的肺部切片.流血是为了流血.

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