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Updated: Jan 17, 2026

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伦达莫西提尼布 (AZD4604) 的首次在人体内进行研究,伦达莫西提尼布是一种吸入性选择性JAK1抑制剂

Tina Jellesmark Jensen1, Camille Riff2, Julia Lund2

  • 1Clinical Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

The Journal of allergy and clinical immunology
|January 14, 2026
PubMed
概括

伦达莫西提尼布是一种选择性的Janus激酶 (JAK) 1抑制剂,在轻度喘患者中有效降低了部分排气的氧化 (FeNO). 吸入药物在第一阶段研究中显示出良好的安全性和耐受性.

关键词:
喘 喘 是一种杰基 (Jakii) 是一个名字.雅努斯酶抑制剂的使用部分排出的氧化氧化物.这是一种炎症炎症炎症炎症.药物动力学 药物动力学目标参与度 目标参与度

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