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Updated: Jan 17, 2026

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
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准拼接因子CWC22通过抑制癌细胞中的BubR1表达和CDK1活性来诱导线粒滑动

Ryuzaburo Yuki1, Youhei Saito1, Yuji Nakayama1

  • 1Laboratory of Biochemistry and Molecular Biology, Kyoto Pharmaceutical University, Kyoto, 607-8414, Japan.

The Journal of biological chemistry
|January 14, 2026
PubMed
概括

剪接因子CWC22通过确保适当的线粒分裂来维持癌细胞的增殖. 准CWC22触发了线粒体滑动和癌细胞死亡,提供了一个潜在的治疗策略.

关键词:
这就是BubR1的意思.根据CWC2222的规定.通过RNA拼接进行RNA拼接.细胞循环中的细胞循环.检查点的控制控制点.循环林依赖性激酶 (CDK) 是一种发生线粒分裂 (mitosis).线粒体的滑动是指线粒体的滑动.

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