儿童早期心血管风险因素和年轻成人认知功能
Henri Salo1,2, Katja Pahkala1,2,3, Harri Niinikoski2,4
1Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Pediatrics
|January 14, 2026
概括
儿童时期的高体重指数和血压等心血管风险因素与年轻人的认知功能较差有关. 早期心血管健康对于在以后的生活中保持认知能力至关重要.
科学领域:
- 发展心理学 发展心理学
- 心血管健康 心血管健康
- 神经科学是一个神经科学.
背景情况:
- 在成年期促进心血管健康有助于预防认知衰退.
- 关于从婴儿期到年轻人的心血管风险因素及其对认知功能的影响的数据有限.
研究的目的:
- 研究从婴儿期到年轻成年期的心血管风险因素与26岁的认知功能之间的关联.
- 了解早期心血管健康对认知表现的长期影响.
主要方法:
- 在特种图尔库冠状动脉风险因素干预项目中,从婴儿期到年轻成年期对参与者的纵向观察.
- 评估心血管风险因素,包括血清脂质,葡萄糖代谢,血压和肥胖指标在定义的发育阶段 (婴儿,童年,青春期).
- 在26岁时测量各种认知功能 (学习,记忆,处理速度,灵活性).
主要成果:
- 儿童和青少年早期更高的体重指数 (BMI) 和腰围与认知灵活性和信息处理相反相关.
- 青春期低密度脂蛋白胆固醇升高与口头记忆力较差有关.
- 儿童时期较低的高密度脂蛋白胆固醇和较高的缩血压与认知灵活性降低有关.
结论:
- 不良的心血管风险概况,包括不良的脂质概况,高BMI,大腰围和从婴儿期到青春期的高血压,与年轻成年人的认知功能下降有关.
- 早期心血管健康在塑造长期认知结果方面发挥着重要作用.
- 研究结果强调了早期和持续促进心血管健康的重要性,以保持认知功能.
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