内镜后食道腺癌:来自哥伦比亚多中心队列的见解
R Castaño-Llano1, L J Palacios2, J R Jaramillo2
1Departamento de Gastroenterología y Endoscopia, Clínica el Rosario, Medellín, Colombia; Departamento de Gastroenterología y Endoscopia, Instituto de Cancerología-Clínica Las Américas AUNA, Medellín, Colombia.
Revista de gastroenterologia de Mexico (English)
|January 14, 2026
概括
末尾镜后食道腺癌 (PEEC) 是常见的,特别是在巴雷特食道 (BE) 患者近端病变. 完善的内镜技术和监测对于高风险个体的早期检测至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜研究 内镜研究
背景情况:
- 食道腺癌 (EAC) 的发病率不断上升.
- 目前内镜查和监测早期发现疾病的局限性,特别是在巴雷特食道 (BE) 的高风险患者中.
- 有关内镜实践导致内镜后食道腺癌 (PEEC) 的准确性的担忧.
研究的目的:
- 为了确定PEEC的发病率.
- 为了分析PEEC的特征.
- 将PEEC患者与初始内镜诊断的患者进行比较,评估BE的作用,并检查病变位置.
主要方法:
- 观察性队列研究.
- 包括哥伦比亚三家医院2012-2023年期间473名食道癌患者.
- 根据STROBE指南对人口,临床和生存数据的评估.
主要成果:
- 在PEEC的比率为6.6%.
- 在PEEC患者中,警报症状较少 (35%与63%相比),BE患病率较高 (42%与23%),早期诊断.
- 内镜错过了靠近的食道病变.
结论:
- PEEC是一个重要的问题,特别是在近端病变的BE患者中.
- 目前的内镜监测可能不足以进行早期检测.
- 需要加强内镜技术和严格的监测协议.
相关概念视频
Barrett Esophagus-II: Clinical Manifestations and Management
796
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
796
Esophageal Varices-II: Clinical Features and Management
374
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
374
Barrett Esophagus-I: Introduction
635
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
635
Endoscopic Procedures I: Esophagogastroduodenoscopy
916
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
916
Esophageal Strictures-II: Clinical Features and Management
432
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
432
Endoscopic Procedures II: Colonoscopy
628
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
628


