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6 - 酸酸脱酶促进线粒体融合和免疫抑制在瘤相关的单细胞抑制细胞

Saeed Daneshmandi1,2, Qi Yan3, Eduardo Cortes Gomez4

  • 1Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Saeed.daneshmandi@roswellpark.org.

Nature communications
|January 14, 2026
PubMed
概括

研究人员发现,阻断6 - 酸酸脱酶 (6PGD) 损害了髓质衍生抑制细胞 (M-MDSCs) 的免疫抑制功能. 这种方法还抑制了瘤的生长,并提高了癌症免疫治疗的结果.

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