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发展耐酒精延长释放配方:监管考虑和配方策略

Ming Ji1, Nitin K Swarnakar2, Shanmuka Harish Chalamuri3

  • 1BASF Corp., Tarrytown, NY, 10591, USA.

Pharmaceutical research
|January 14, 2026
PubMed
概括

这项研究开发了使用聚乙烯 (PVAc) 和聚乙烯 (PVP-90) 的延长释放 (ER) 配方,以防止酒精诱导的剂量倾销 (ADD). 优化的配方显示ADD风险降低,并且即使在储存后也保持了ER概况.

关键词:
增加的指导方针ADD.酒精耐药性 耐酒性 耐酒性酒精诱导的剂量倾销 (ADD)聚乙烯酸 (PVAc) 分散的分散.聚乙烯罗利 (PVP) 90 90 聚乙烯罗利储类型的延长释放配方持续释放涂层的持续释放涂层

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