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基于智能手机的血管运动功能的评估通过指尖动脉弹性使用体积振荡计方法与绿色光照相传感仪
Takehiro Yamakoshi1,2, Peter Rolfe3,4, Ken-Ichi Yamakoshi5,6,7
1Institute of Liberal Arts and Science, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, 9201192, Japan. takehiroy@me.com.
Annals of biomedical engineering
|January 14, 2026
概括
一种新的智能手机方法非侵入性地测量指尖动脉弹性,以评估血管运动功能. 这种技术可以通过方便的自我评估来早期检测心血管疾病的风险因素.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 血管运动功能对于血压调节和器官输液至关重要.
- 功能障碍的血管运动活动是心血管疾病的重要危险因素.
- 目前用于评估血管运动功能的方法缺乏非侵入性,量化和可访问性.
研究的目的:
- 开发和验证一种基于智能手机的新技术,用于评估血管运动活动.
- 用智能手机非侵入性地测量指尖动脉弹性.
- 为了解决对评估血管运动功能的定量和可访问方法的需求.
主要方法:
- 使用了一款带有绿光光电显微镜 (gPPG) 的智能手机.
- 将智能手机与可拆卸的指尖压缩装置相连,用于体积振荡计测量.
- 测量了动脉动脉血压,硬度和延展能力,作为延展压力的函数.
- 通过冷刺激诱导血管收缩,用于方法验证.
主要成果:
- 在13名健康志愿者中成功量化了动脉动脉血压和弹性指数.
- 在感冒引起的血管收缩期间观察到显著增加的刚性和延展能力的下降 (p < 0.01).
- 证明与预期的血管收缩反应一致.
结论:
- 基于智能手机的方法是评估血管运动活动的可行,实用,非侵入性和可访问的工具.
- 需要在更大的队列中进一步验证.
- 这种方法有可能通过自我评估来早期检测血管运动功能障碍和预防心血管疾病.
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