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Updated: Jan 16, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Published on: June 21, 2018

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在44,287名多祖先参与者中对肺功能和COPD进行全基因组序列分析

Wonji Kim1, Xiaowei Hu2, Kangjin Kim1,3

  • 1Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.

Genome biology
|January 15, 2026
PubMed
概括

在不同人群中进行大规模的全基因组测序,发现了与慢性阻塞性肺病 (COPD) 和肺功能相关的新遗传变异. 这项研究提高了我们对COPD遗传学和潜在治疗点的理解.

关键词:
慢性慢性肺炎是一种慢性慢性肺炎,COPD是一种慢性肺炎.克里斯普尔的淘汰,是因为它破坏了CRISPR.用分子QTLs进行局部化.精细地图的绘制.肺功能 肺功能 肺功能肺组织单细胞RNA-seq验证.多种祖先的GWAS.

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Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function02:09

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