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Updated: Jan 16, 2026

A Plate-Based Assay for the Measurement of Endogenous Monoamine Release in Acute Brain Slices
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在经批准的药物中,对膀单胺转运体2 (VMAT2) 抑制和神经学不良事件之间的关系的评估

Rebecca Racz1, Laura B Kozell2,3,4, Amy J Eshleman2

  • 1Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States.

ACS pharmacology & translational science
|January 15, 2026
PubMed
概括

这项研究选了257种化合物的囊泡单胺转运体2 (VMAT2) 抑制,发现许多药物影响多巴胺吸收. 在VMAT2抑制和报告的神经精神事件之间没有发现直接联系.

关键词:
已批准的药物是药物.多巴胺吸收的时间神经学不良事件 神经学不良事件神经学不良事件 神经学不良事件这些神经递质是神经递质.囊泡单胺转运体 (VMAT2) 是一种

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