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Updated: Jan 16, 2026

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埃梅斯特林类型的epidithiodiketopiperazines通过卡斯帕斯-3/7激活抑制了D介导的气体皮质死

Bingchuan Geng1,2,3,4, Shuang Lin1,5, Wai Yen Yim4

  • 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy Tongji Medical College, Huazhong University of Science and Technology Wuhan China.

MedComm
|January 15, 2026
PubMed
概括

埃梅斯林类型的epidithiodiketopiperazines (ETPs) 抑制了Gasdermin D (GSDMD) 的裂变,减少了热和炎症. 化合物2在败血症模型中显示出治疗潜力,改善生存率和抑制炎症细胞透.

关键词:
灭症 (apoptosis) 是一种死亡的过程.气体皮层 D D D D D高通量选的高通量选热致灭症是什么?这是一种血症.

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