冠状动脉评分作为心血管疾病事件和无症状工作年龄成年人死亡率的预测指标:系统性审查
Marinos Charalambous1, Robert Filler2, Elpidoforos S Soteriades3
1Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, CYP.
Cureus
|January 15, 2026
概括
冠状动脉 (CAC) 评分有效预测无症状的劳动年龄成人心血管疾病 (CVD) 事件和死亡率. 超过零的CAC分数表明风险明显增加,较高的分数与更大的危险相关.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 医疗成像医学成像
背景情况:
- 冠状动脉 (CAC) 评分有助于无症状个体心血管疾病 (CVD) 的风险分层.
- 它的实用性特别重要,当他类药物的开始或加强的初级预防是不确定的.
- 对工作年龄的成年人来说,评估CAC得分的预测价值对于早期干预至关重要.
研究的目的:
- 系统地审查CAC评分对CVD事件和死亡率的预测能力.
- 评估CAC评分在18-65岁无症状成年人中的有效性.
- 为了比较CAC评分的歧视力与传统的风险评分.
主要方法:
- 对2009年11月至2022年12月期间发表的研究进行系统审查.
- 纳入标准侧重于18-65岁的无症状成年人.
- 分析了符合审查标准的四项选定的研究.
主要成果:
- 任何CAC得分大于零都与心脏事件的4-5倍风险增加有关.
- 观察到一种剂量-反应关系,其中较高的CAC得分与心脏事件和死亡率的风险增加相关.
- 与Framingham和ASCVD风险评分相比,CAC评分显示出所有原因死亡率的优越歧视力.
结论:
- CAC评分是对无症状的劳动年龄成年人心血管疾病事件和死亡率的有价值的预测指标.
- CAC评分在识别高风险个体方面表现有前途.
- 需要进一步的前性研究来评估CAC评分作为一般选工具的成本效益.
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