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Updated: Jan 16, 2026

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
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Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes

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[准调控性T细胞来重塑周围免疫耐受性:研究进展和未来方向]

Wei Zhang1, Zhenhong Li1, Hantian Liang1

  • 1（ 610041） State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
|January 15, 2026
PubMed
概括

调节性T细胞 (Tregs) 对免疫耐受性至关重要. 对炎症性疾病而言,Treg疗法具有前景,但在临床转化方面面临挑战,需要进一步研究稳定性,特异性和安全性.

关键词:
自身免疫性疾病是一种自身免疫性疾病.狐p3p3 在线观看移植对宿主疾病 (GVHD) 是一种移植对宿主疾病.免疫治疗是一种免疫疗法.低剂量互白素-2疗法治疗监管T细胞疗法规定的T细胞疗法审查 审查 审查 审查

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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