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林蒂戈恶性:当代手术管理和结果:一篇综述
Carmen Cánovas Seva1, Lorena Martínez Leboráns1, Ana Batalla1
1Dermatology Department, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15700 A Coruña, Spain.
Annali italiani di chirurgia
|January 15, 2026
概括
像莫斯微图外科手术 (MMS) 这样的边际控制的手术技术,与宽局部切除 (WLE) 相比,可以提供更优质的局部控制阴茎恶性 (LM). 手术方法的选择取决于各种因素,优先考虑患者的结果和资源的可用性.
科学领域:
- 皮肤病学和瘤学
- 手术病理学手术病理学
背景情况:
- 阴茎恶性瘤 (LM) 是一种常见的黑色素瘤 in situ 变体,发生在阳光损伤的皮肤上.
- 亚临床扩散和异型症复杂化手术清除和LM的组织学解释.
研究的目的:
- 评估当代手术选择的LM:宽局部切除 (WLE),莫斯微图手术 (MMS),慢莫斯,和分阶段切除 (SE).
- 为了比较这些手术技术的瘤学结果,为LM.
主要方法:
- 对LM/LMM手术技术和结果的研究进行了全面的文献搜索 (PubMed, Web of Science, Jan 2015-Jan 2025).
- 46项检索研究的定性综合,包括回顾性队列,系统性审查和元分析.
主要成果:
- WLE显示出高异质性,其残留疾病率高达16.7%,复发率从5.7%到27.3%.
- 在≥5年的随访期内,MMS的复发率较低 (0-3%),特别是在免疫组织化学研究中.
- 慢莫斯和SE提供了中间控制 (0-5.7%),但具有程序变化和延迟重建.
结论:
- 边际控制技术 (MMS,慢Mohs,SE) 为LM提供了对WLE的优越局部控制,特别是在关键的美容/功能部位.
- 技术选择应平衡解剖位置,病变大小,专业知识,患者因素和资源,因为生存似乎相当.
- 需要使用标准化方案进行前性试验,以改进边际建议并比较长期结果.
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