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Updated: Jan 16, 2026

Fibroblast-Derived 3D Matrix System Applicable to Endothelial Tube Formation Assay
07:21

Fibroblast-Derived 3D Matrix System Applicable to Endothelial Tube Formation Assay

Published on: December 26, 2019

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Grhl3下调有助于纤维细胞的ECM适应ICM承诺

Xin Wu1,2,3, Lanbing Liu1,2,3, Yuanru Huang1,2,3

  • 1Department of Cardiology, Zhongnan Hospital of Wuhan University, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Wuhan University, China. (X.W., L.L., Y.H., Y.L., F.L., M.L., Z.J., Z.Y., X.K., Y.W., L.W.).

Circulation research
|January 15, 2026
PubMed
概括

直接的心脏重编程将纤维细胞转化为心肌细胞,用于心脏修复. 准Ghrhl3,这是细胞外矩阵重塑的关键调节器,增强了这一过程,改善了心肌梗塞后的心脏功能.

关键词:
细胞的可塑性 细胞的可塑性细胞外矩阵是细胞外矩阵.心肌梗塞的心脏病发作肌细胞心脏 肌细胞心脏改变增长因素的转变.

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