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Updated: Jan 16, 2026

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
09:03

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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GPCRact:通过全沟通建模预测连接体诱导的GPCR活动的层次框架

Hyojin Son1, Gwan-Su Yi1

  • 1Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

Briefings in bioinformatics
|January 15, 2026
PubMed
概括

GPCRact通过使用新型图形神经网络框架模拟全沟通来准确预测G蛋白结合受体活性,从而改善药物发现. 这种方法捕捉复杂的3D动态,以更好地进行结构导向设计.

关键词:
与G蛋白结合的受体 (GPCRs) 是一种全osteric 沟通 通讯 的所有性.发现药物的发现.图表神经网络的神经网络可解释的人工智能AI

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