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Updated: Jan 17, 2026

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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包装驱动的机械传导:局部拥挤取代了细胞集体中YAP激活的粘附和刚性线索

Valeriia Grudtsyna1, Vinay S Swaminathan2,3, Amin Doostmohammadi1

  • 1Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, 2100 Copenhagen, Denmark.

Journal of the Royal Society, Interface
|January 15, 2026
PubMed
概括

细胞包装密度,而不是单个细胞的力量,控制着细胞群中的YAP激活. 这一发现揭示了细胞集体如何调节机械传导,影响了组织工程和癌症研究.

关键词:
这是E-cadherin.是的 - 相关蛋白质.活动性细胞骨集体机械传导集体机械传导当地的包装分数核的形状 核的形状基板的硬度 基板的硬度

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