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下一代CAR-T治疗急性髓性白血病:将创新与临床翻译相结合

Xumeng Zhao1, Xi Ming1, Jiaying Wu1

  • 1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Annals of hematology
|January 15, 2026
PubMed
概括

化学抗原受体 (CAR) T细胞疗法在急性髓性白血病 (AML) 中面临挑战,原因是毒性和T细胞耗尽. 在CAR设计和T细胞调制方面的创新旨在克服这些障碍,以改善AML治疗.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.适配器 CAR-T 细胞一种全基性CAR-T细胞.在CAR-T疗法中,基因编辑 基因编辑有逻辑门的CAR-T细胞

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