追踪持久和耐药的Enterococcus faecalis和E. faecium从一个农场到另一个农场:与生物膜相关的风险在分离的抗生素耐药性
Kursat Koskeroglu1, Nurhan Ertas Onmaz2, Dursun Alp Gundog3
1Department of Veterinary Public Health, Faculty of Veterinary Medicine, Erciyes University, 38039, Kayseri, Türkiye.
Veterinary research communications
|January 15, 2026
概括
肉类中的Enterococcus faecalis和E. faecium菌株对抗生素具有耐药性,并形成生物膜,构成高风险. 农场卫生和合理的抗生素使用对于食品安全至关重要.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 兽医公共卫生 兽医公共卫生
背景情况:
- 菌 (Enterococcus faecalis) 和菌 (Enterococcus faecium) 是重要的食物传播病原体.
- 这些细菌的抗微生物耐药性和生物膜形成越来越令人担忧.
研究的目的:
- 调查肉类生产链中E. faecalis和E. faecium的流行,抗微生物耐药性,生物膜形成,毒性基因和风险水平.
- 评估这些肠球菌对食品污染的贡献,以及它们作为耐药性和毒性存储库的作用.
主要方法:
- 从肉样本中分离和识别肠球菌物种.
- 抗微生物敏感性测试,包括对四环素,红红素,万科素和西普罗夫洛克萨的耐药性.
- 评估生物膜形成能力和检测毒性基因 (gelE, efa).
- 对于孤立的肠球菌的风险评估评分.
主要成果:
- 肠球菌 (Enterococcus spp.) 是一种细菌. 在60%的样本中发现,其中E. faecalis (20%) 和E. faecium (23%) 是普遍存在的.
- 观察到对四环素和红素的耐药性高;对万素和西普罗夫洛素的耐药性低,但与多药耐药性 (MDR) 相关.
- 所有分离物形成生物膜,其中55%是携带gelE和/或efa基因的强有力的生产者,与较高的MDR率相关.
- 高达40%的分离物被归类为高风险.
结论:
- 肉类生产连续中的肠球菌是抗菌素耐药性和毒性因素的重要来源.
- 强大的生物膜形成与这些病原体的多药耐药性增加有关.
- 有效的农场级卫生,明智的抗生素使用和有针对性的监测对于减轻"一个健康"方法中的风险至关重要.
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