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Updated: Jan 17, 2026

An Efficient Strategy for Generating Tissue-specific Binary Transcription Systems in Drosophila by Genome Editing
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转子子衍生调节元素的组织特异性限制可以保证细胞类型的身份

Danica Milovanović1, Julien Duc1, Wayo Matsushima1

  • 1School of Life Science, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Cell reports
|January 15, 2026
PubMed
概括

KRAB指蛋白 (KZFPs) 调节可转移元素 (TE) 独立于TRIM28. ZNF436通过控制TE衍生的调节元件来保护心脏细胞的身份,揭示了新的KZFP功能.

关键词:
CP: 发育生物学科普:分子生物学 分子生物学KRAB 的指蛋白质线路/L2 在线这就是SINE/MIR.在 SWI/SNF 中.心肌细胞分化的心肌细胞分化.染色体重塑 染色体重塑 的方法这些是cis-regulatory元素.增强剂是一种增强剂.可转移的元素可以转移.

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