Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Dose-Response Relationship: Overview01:03

Dose-Response Relationship: Overview

4.9K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
4.9K
Drug Dependence01:17

Drug Dependence

1.6K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.6K
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

1.7K
Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
1.7K
Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

181
Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...
181
Drug Discovery: Overview01:26

Drug Discovery: Overview

11.0K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
11.0K
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

495
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
495

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Implementation Evaluation of a Multicomponent Intervention to Address the Infectious Disease and Overdose Syndemic Among People Who Use Drugs in Rural Settings.

Journal of public health management and practice : JPHMP·2026
Same author

Deep learning for time-series segmentation of mechanical ventilator waveforms.

Scientific reports·2026
Same author

Falls and Fall-Related Injuries and Hospitalizations in Autistic Older Adults: A Medicare Data Study.

Autism : the international journal of research and practice·2026
Same author

The Estimated Benefit of Lights and Sirens During Ambulance Transport.

Prehospital emergency care·2026
Same author

Risk of dementia and related neurocognitive disorders among autistic and non-autistic older adults: role of established risk factors.

Age and ageing·2026
Same author

A Pragmatic Randomized Controlled Trial of Ambient Artificial Intelligence to Improve Health Practitioner Well-Being.

NEJM AI·2026

相关实验视频

Updated: Jan 17, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K

设计药物滥用数据仪表板用于过量致死性审查团队:以用户为中心的设计方法

Marie Pisani1, Madeline K Oguss2, Julia Dickson-Gomez3

  • 1Department of Medicine, University of Wisconsin, Madison, WI, United States.

JMIR human factors
|January 15, 2026
PubMed
概括
此摘要是机器生成的。

一个新的仪表板通过整合数据源来简化过量致死性审查 (OFR),减少公共卫生专业人员的手工工作量和认知压力. 该工具提高了识别过量预防策略的效率.

关键词:
数据链接数据链接过量服用过量服用过量公共卫生信息学 公共卫生信息学定性研究是指质量研究.药物使用障碍 药物使用障碍

更多相关视频

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq
04:54

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq

Published on: March 19, 2021

5.1K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.5K

相关实验视频

Last Updated: Jan 17, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K
Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq
04:54

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq

Published on: March 19, 2021

5.1K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.5K

科学领域:

  • 公共卫生信息学 公共卫生信息学
  • 数据可视化 数据可视化
  • 人类因素工程 人类因素工程

背景情况:

  • 过量使用致死率审查 (OFR) 对于确定过量使用预防策略至关重要,但由于数据来源分散,需要大量的劳动力.
  • 药物滥用数据共享 (SMDC) 平台整合了各种数据,但缺乏OFR的可视化工具.
  • 目前的OFR流程涉及大量的手工工作和认知工作量,包括数据分析和案例准备.

研究的目的:

  • 为SMDC平台开发一个全面的数据可视化仪表板.
  • 应用人类因素设计原则来优化OFR流程.
  • 提高过量致死性审查的效率和有效性.

主要方法:

  • 调查了使用NASA任务负载指数来评估认知工作负载的OFR领导者.
  • 进行半结构面试以确定工作流优化目标.
  • 使用GPT-4合成数据开发了原型仪表板,随后进行了代设计,启发式评估以及通过调查和采访 (UTAUT,PUQ) 获得最终用户反.

主要成果:

  • 目前的OFR任务显示了中度高的心理工作量 (NASA-TLX得分为12).
  • 原型仪表板整合了多个数据源,生成了人口级别的可视化和患者级别的时间表.
  • 最终用户预计效率和数据可访问性有所提高;仪表板显示了高的采用潜力 (UTAUT平均值4.07/5) 和中等的有用性 (PUQ平均值~3.6/5).

结论:

  • 开发的仪表板提供了一个以用户为中心,基于信息学的解决方案,以简化OFR中的数据聚合和呈现.
  • 实施这种仪表板可以显著减轻与OFR相关的手工工作量和认知负担.
  • 该工具旨在为OFR领导人提供增强的能力,以开发干预措施来减少过量死亡.