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相关概念视频

Atomic Force Microscopy01:08

Atomic Force Microscopy

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Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
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相关实验视频

Updated: Jan 17, 2026

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
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Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

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非近距离,手持式探测器具有位置反,用于实时分析三维物体表面的三维物体表面.

G Asher Newsome1

  • 1Smithsonian Museum Conservation Institute, Suitland, Maryland 20746, United States.

Journal of the American Society for Mass Spectrometry
|January 15, 2026
PubMed
概括

一个新的灵活的子转移管提高了非近距离脱吸光离子化 (NPDPI) 分析. 该系统最大限度地减少了分析物损失,并使复杂表面在没有直接视线的情况下进行实时分析.

科学领域:

  • 分析化学 分析化学
  • 频谱学是一种光谱学.
  • 材料科学 材料科学 材料科学

背景情况:

  • 非近距离质谱技术经常遭受分析物损失和信号传递.
  • 现有的方法使用未加热的塑料管,导致从遥远的表面取样有机分析物的效率低下.

研究的目的:

  • 开发一种灵活高效的非近距离脱吸光电离 (NPDPI) 转移系统.
  • 为了实时分析复杂和难以接近的表面几何形状的分析物.

主要方法:

  • 实施了一种新的子转移管设计,提供灵活性和减少分析剂吸附.
  • 为了方便用户操作,开发了带有加热气体喷射和接触传感器的集成脱吸探头.
  • 中性去吸附的分析物被转移到4米远的多光电离源.

主要成果:

  • 与传统的塑料管相比,新的子管显著减少了有机分子损失.
  • 实时分析成功地在具有狭窄尺寸和盲目形几何形状的表面上进行了演示.
  • 从各种常见的物体中检测到挥发性和不可挥发性分析物.

结论:

  • 灵活的NPDPI系统克服了以前非近距离采样技术的局限性.
关键词:
这是NPDPI的NPDPI.环境采样环境采样消极化是一种被动化.光电离子化是指光电离子化.热溶解脱吸方式

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  • 这一进步允许对具有挑战性的样本表面进行高效和清洁的分析.
  • 这项技术有望在痕迹分析剂检测和表面表征方面扩大应用.