与加拿大相比,阿尔伯塔省,萨斯喀彻温省和马尼托巴省的C型肝炎流行病学,1980-2023年
Zipporah Gitau1, Camilo Suarez-Ariza1, Maria Arango-Uribe1
1Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.
Journal of infection and public health
|January 15, 2026
概括
加拿大型肝炎 (HCV) 发病率正在下降,但曼尼托巴和萨斯喀彻温州的发病率较高,与使用物质有关. 协调的监测和预防工作对于消除HCV至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 加拿大的目标是到2030年消除C型肝炎病毒 (HCV),但区域差异仍然存在.
- 曼尼托巴和萨斯喀彻温州的HCV发病率特别高,超过了全国平均水平.
- 了解HCV发病率和风险因素的省级变化对于有针对性的干预至关重要.
研究的目的:
- 描述阿尔伯塔省,萨斯喀彻温省和马尼托巴省HCV感染的发病率和确定风险因素.
- 将这些草原省的HCV趋势与1980年至2023年的全国数据进行比较.
- 为公共卫生策略提供信息,以控制和消除HCV.
主要方法:
- 一个生态研究设计,利用公开可用的政府报告从1980-2023.
- 分析的数据包括HCV病例和发病率,按性别,年龄,种族,省份,性取向和风险因素进行分类.
- 研究的关键风险因素包括注射药物使用,血液产品暴露和监禁史.
主要成果:
- 虽然自1991年以来全国HCV发病率有所下降,但自2005年以来,萨斯喀彻温省的发病率一直高于平均水平.
- 曼尼托巴省在2021年报告了全国最高的HCV病例率 (42.8/100,000),而阿尔伯塔省的病例率最低 (14.5/100,000).
- 注射药物使用是萨斯喀彻温省和马尼托巴省的主要风险因素;在这些省份,年轻人越来越受到影响.
结论:
- 加拿大的HCV病例呈下降趋势,但曼尼托巴和萨斯喀彻温省的高发病率值得关注.
- 药物使用综合症可能会导致这些地区的HCV,HIV和其他STBBI的发病率更高.
- 在HCV监测,检测,治疗和预防方面,省级协作努力至关重要.
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