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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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优化患者报告的沙尔科毒症结局.

Vivienne Kahlmann1, Donald Simon2, Marlies S Wijsenbeek1

  • 1Centre of Excellence for Interstitial Lung Diseases and Sarcoidosis, Department of Respiratory Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

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科学领域:

  • 肺部医学 肺部医学
  • 类风湿病学 类风湿病学
  • 免疫学 免疫学 免疫学

背景情况:

  • 肉病呈现出各种症状,影响患者的生活质量 (QoL).
  • 身体质量是肉病患者的关键治疗优先事项.
  • 测量患者的症状体验至关重要,但具有挑战性.

研究的目的:

  • 审查通常使用的通用和特定疾病的患者报告的结局措施 (PROMs) 对于型硬化症.
  • 总结一下这些PROM的心理测量特性.
  • 讨论PROM在 Sarcoidosis中的使用局限性和未来方向.

主要方法:

  • 关于PROMs在肉类发病中的文献综述.
  • 对心理测量属性的分析 (有效性,可靠性,响应性).
  • 关于PROM在临床试验和实践中的应用发现的综合.

主要成果:

  • 概述经常使用的通用和特定于sarcoidosis的PROMs.
  • 现有措施的心理测量优点和弱点的总结.
  • 识别PROM开发和实施的差距和机会.

结论:

  • PROMs是评估类病患者体验和治疗有效性的重要工具.
  • 需要根据心理测量特性仔细选择PROM.
  • 进一步的研究应侧重于完善现有的PROM,并开发适合 Sarcoidosis 的新的PROM.