与尿路阻塞相关的Oligella urethralis 细菌病:一个病例报告和文献综述
Emiri Muranaka1, Mutsuka Kurihara1, Naoki Okawa2
1Department of Infectious Diseases, Japanese Red Cross Narita Hospital, Chiba, Japan.
概括
奥利格拉尿道菌 (Oligella urethralis) 是一种罕见的格拉姆阴性菌,可在患有阻塞性尿路病的老年患者中引起细菌病. 早期识别和适当的抗生素是有利结果的关键,尽管存在潜在的诺基诺隆耐药性.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 奥利格拉尿道菌 (Oligella urethralis) 是一种格拉姆阴性菌,通常是正常泌尿器官菌群的一部分.
- 它可以引起机会性感染,特别是在免疫力低下的人或患有潜在疾病的人身上.
- 与杆状细菌相比,O. urethralis很少被确定为尿路病原体.
研究的目的:
- 报告一个患有尿路结石的老年男性患有O. urethralis bacteremia的病例.
- 审查和分析之前报告的O. urethralis bacteremia的病例.
- 要突出确定O. urethralis作为病原体的临床意义.
主要方法:
- 一个74岁的男性患有急性肺炎和细菌血症的病例报告.
- 使用MALDI-TOF从血液和尿液培养物质谱法识别O. urethralis.
- 在1987年至2025年5月期间发表的O. urethralis bacteremia病例的文献搜索.
主要成果:
- 该病例患者出现了急性炎症和细菌病,发现了O. urethralis.
- 总共分析了7个病例 (包括目前的病例),所有病例都发生在老年患者中 (平均年龄为79岁),这些患者患有诸如阻塞性尿路病变等倾向性疾病.
- 预后总体上是有利的,有一个死亡不是直接归因于O. urethralis感染.
结论:
- 在患有阻塞性尿路病变和细菌病的老年患者中,Oligella urethralis应被视为潜在的病原体.
- 对O. urethralis的认识对于适当的抗微生物选择至关重要,因为常见的诺基诺隆耐药性.
- 对O. urethralis进行的抗微生物敏感性测试的解释挑战需要临床警.
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