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Updated: May 6, 2026

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
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Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

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胚胎乙醇暴露对斑马鱼基因表达和执行功能的长期影响

Romério de Oliveira Lima Filho1, Ricardo Gabriel de Lima Bisneto2, Beatriz Silva do Nascimento2

  • 1Fish Lab, Department of Physiology and Behavior, Biosciences Center, Graduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, RN, Brazil; Department of Cell Biology and Genetics, Biosciences Center, Graduate Program in Biotechnology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Progress in neuro-psychopharmacology & biological psychiatry
|January 15, 2026
PubMed
概括

斑马鱼的胚胎乙醇暴露会导致持久的认知缺陷和改变基因表达,影响神经发育. 这些发现凸显了对胎儿酒精谱系障碍 (FASD) 产前酒精意识和干预措施的关键需求.

关键词:
认知灵活性 认知灵活性丹尼奥·雷里奥 (Danio Rerio) 是一个多巴氨基信号传递.胎儿酒精谱系障碍 胎儿酒精谱系障碍

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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