不同CT输液软件对缺血性中风患者分层策略的影响
Fabio Tortora1, Eduardo Gragnano2, Sirio Cocozza1
1From the Department of Advanced Biomedical Sciences (F.T., S.C., F.G., M.R., G.B., A.M., S.P., F.B.), University of Naples "Federico II", Naples, Italy.
AJNR. American journal of neuroradiology
|January 15, 2026
概括
分析计算机断层扫描输液 (CTP) 数据的不同软件显著影响缺血性中风核心体积估计和患者适应内血管治疗 (EVT) 的资格. 对这些差异的认识对于临床决策至关重要.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 医学成像分析 医学成像分析
背景情况:
- 计算机断层扫描输液 (CTP) 软件变体存在用于分析缺血性中风.
- 不同的CTP软件在临床实践中的可比性和可互换性仍未得到充分探索.
- 准确估计缺血核心体积对于患者分层至关重要.
研究的目的:
- 为了比较两个不同的商业CTP软件解决方案 (Viz.ai和syngo.via) 的性能.
- 评估软件差异对缺血性核心体积估计的影响.
- 评估软件可变性对患者内血管治疗分层 (EVT) 的影响.
主要方法:
- 一项回顾性单心观察性研究包括109名缺血性中风患者.
- 用DAWN和DEFUSE-3标准进行患者分层.
- 两个软件程序 (Viz.ai,syngo.via) 使用各种相对脑血流 (CBF) 值进行了比较.
主要成果:
- 在两种软件程序之间观察到缺血核心体积识别的显著差异 (P < .001).
- 软件选择导致基于DAWN标准的患者排除在EVT之外的情况显著增加 (P = .005).
- 使用更保守的CBF值减少了,但没有消除软件之间的差异 (P = .68).
结论:
- CTP软件和值的变化可能导致中风患者的核心体积估计和治疗分层显著不同.
- 医生在解释CTP数据时必须意识到这些软件诱导的差异.
- 了解这些差异对于有关EVT资格的知情临床决策至关重要.
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