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Updated: Jan 17, 2026

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PP2A激活的目标是神经母细胞瘤中的MYCN

Nazia Nazam1, Shamza Manzoor2, Maryam Shaikh1

  • 1Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Cell death & disease
|January 15, 2026
PubMed
概括

赛林/氨酸蛋白酸酶2A (PP2A) 的药理活性降低了高危神经母细胞瘤 (HR-NBL) 中的MYCN表达和瘤生长. 这表明PP2A激活剂是HR-NBL的潜在治疗策略.

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