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Updated: Jan 17, 2026

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
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人类COP1-DET1无素合酶复合物的冷EM结构

Shan Wang1,2, Fei Teng1,2,3, Goran Stjepanovic3

  • 1Department of Biochemistry, SUSTech Homeostatic Medicine Institute, School of Medicine, Southern University of Science and Technology, Shenzhen, China.

Nature communications
|January 15, 2026
PubMed
概括

该COP1 E3结合酶复合体经历结构变化以激活基质无化. 这项研究揭示了COP1和DET1复合体如何重新排列以结合和修改基质,为无处不在调节提供了洞察力.

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