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Updated: Jan 18, 2026

Reconstitution of Msp1 Extraction Activity with Fully Purified Components
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Tmem110调节TRPML1的构造,以维持内分泌体平衡,并防止线粒体DNA泄漏和病态的自我DNA处理

Zunyong Feng1, Yuanbo Pan2, Jing Zhou3

  • 1State Key Laboratory of Macromolecular Drugs and Large-scale Preparation, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China. fengzy@wmu.edu.cn.

Nature communications
|January 15, 2026
PubMed
概括

在创伤性脑损伤后,细胞内膜网膜调节器TMEM110对于清除受损的线粒体至关重要. 它的缺失会通过破坏 lysosomal 功能来恶化器官功能障碍和自身免疫反应.

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