加强母乳的强化,以达到早产婴儿营养目标
Ting Ting Fu1,2, Carla M King3, Jae H Kim3,4
1Division of Neonatology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. tingting.fu@cchmc.org.
Pediatric research
|January 16, 2026
概括
对于早产婴儿来说,增强母乳强化始终符合蛋白质摄入目标,是标准强化的有效替代品. 母乳,有或没有强化,更有可能达到脂肪摄入目标.
科学领域:
- 新生儿营养新生儿营养
- 婴儿的成长和发展.
背景情况:
- 过早出生的婴儿往往需要营养超过标准强化 (24 kcal/oz) 足够的增长.
- 个性化防御改善了增长,但资源密集.
- 对于出生时体重非常低的婴儿,实施了全方位增强强化强化 (26 kcal/oz).
研究的目的:
- 评估捐赠母乳 (DBM) 和增强强化母乳 (MBM) 的营养充足度.
- 为了比较强化和标准强化方法之间的营养目标实现.
主要方法:
- 对出生小于1500克和小于33周的婴儿进行前性队列研究.
- 使用中红外分析分析MBM和DBM宏观营养素含量的分析.
- 营养摄入目标 (脂肪,碳水化合物,蛋白质) 与标准和增强强固化的比较.
主要成果:
- 与DBM相比,MBM表现出较高的蛋白质,脂肪和能量含量 (p<0.0001).
- 无论强化方法如何,MBM样本更频繁地达到脂肪摄入目标.
- 强化强化显著提高了蛋白质目标的实现,所有样本达到3.5-4g/kg/day,56%达到4.5g/kg/day.
结论:
- 增强强化是实现早产婴儿肠道营养目标的有效和可行的方法.
- 增强强化始终提供比标准强化更高的蛋白质摄入量,特别是与DBM.
- 母乳更有可能达到脂肪摄入目标,但可能需要根据强化剂成分进行额外的丰富.
相关概念视频
Development of Immunocompetence
793
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
793
Drug Dosing: Infants and Children
256
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
256
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
853
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
853


