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在慢性喘模型中,IL-36通过诱导表皮层-介质细胞过渡过程,参与了呼吸道重塑

Min Zhang1,2, Jiemei Cen1, Wenlei Gan1

  • 1Department of Pulmonary and Critical Care Medicine, Institute of Respiratory Disease of Sun Yat-Sen University, Third Affiliated Hospital of Sun Yat-Sen University, Tianhe Road 600, Guangzhou, 510630, Guangdong, China.

European journal of medical research
|January 16, 2026
PubMed
概括

干白素-36 (IL-36) 通过诱导上皮层-介质细胞过渡 (EMT) 来促进严重喘中的呼吸道重塑. 阻断IL-36信号减轻了与喘相关的气道改造和炎症,这表明IL-36是潜在的治疗点.

关键词:
气道改造 气道改造 气道改造喘 喘 是一种在EMT中,EMT是EMT.在IL-36中,IL-36是最常见的.

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