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在日本老年人群中,状动脉内膜介质厚度与萨科佩尼亚之间的纵向关联:SONIC研究

Ken Terashima¹, Hiroshi Akasaka^1,2, Yuri Onishi¹

¹Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Geriatrics & gerontology international

|January 16, 2026

概括

动脉内心介质厚度增加 (CIMT) 与老年人肉症有关. 这一发现表明,CIMT可以作为一种有价值的标记物,用于识别患有沙科佩尼亚风险较高的个体.

科学领域:

老年学是一门学科.
心血管医学心血管医学
营养科学营养科学

背景情况:

老年人中常见的 Sarcopenia 疾病与不良健康结果有关,包括增加死亡率和长期护理需求.
石症和心血管疾病有着双向的关系,每一种情况都可能加剧另一种情况.

研究的目的:

在老年人群中调查动脉内膜介质厚度 (CIMT) 和肉症之间的关联.
探索CIMT和肉症之间的横截面和纵向关系.

主要方法:

利用了来自七十岁,八十岁,非百岁调查与百岁 (SONIC) 研究的数据.
采用了第三波数据的横截面分析和第四波 (3年后) 萨科佩尼亚状态的纵向分析,与基线CIMT相关.
根据亚洲肉病工作组 (AWGS) 2019年指导方针诊断出肉病.

主要成果:

横截面分析包括735名参与者,其中17.7%被诊断为肉类. 最大CIMT增加1毫米与肉症的几率比率 (OR) 为1.55有关.
这项纵向研究涉及498名参与者. 基线最大CIMT增加1毫米与三年后发展肉症的OR为1.63有关.
两项分析都表明,较高的CIMT与肉类的存在或发展之间存在统计学上显著的关联.

结论:

冠状动脉内心介质厚度 (CIMT) 与老年人肉症显著相关.
这些发现有助于了解血管健康和肌肉质量之间的病理生理学.
CIMT显示出作为一种非侵入性标记物的潜力,用于识别具有高风险的萨尔科佩尼亚个体.

关键词:

心血管疾病心血管疾病动脉内心介质厚度动脉内心介质厚度纵向研究是一种纵向研究.老年人年长的人.这种类型的麻症是sarcopenia.

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