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Updated: Jan 18, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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对NK细胞受体的静止状态空间统计可能会改善早期信号歧视

Saeed Ahmad1, Debangana Mukhopadhyay1, Rajdeep Grewal1

  • 1Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus OH.

Biophysical journal
|January 16, 2026
PubMed
概括

自然杀手 (NK) 细胞受体形成团,有助于区分健康细胞和患病细胞. 它们的空间布局是免疫细胞准确感知目标细胞的关键.

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T Cell Activation and Clonal Selection01:22

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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