高度是否对中风死亡率和住院风险有影响? 对美国数据进行全面评估
Jacob Gerken1, Nathan Huber1, Demi Zapata1
1Department of Biomedical Sciences, Rocky Vista University, Parker, CO, United States.
Frontiers in stroke
|January 16, 2026
概括
高度在不同种族群体中不同影响中风死亡率,对白人群体有保护作用,但对西班牙裔和亚太地区人口有不利影响. 环境因素显著影响心血管疾病和中风的结果.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心血管疾病研究研究
背景情况:
- 在全球范围内,中风是导致死亡的主要原因,特别是在50岁以上的人群中.
- 环境因素,如高度,可能会影响中风的结果,但需要进一步调查.
- 了解这些因素对于解决健康差异至关重要.
研究的目的:
- 评估高度对美国成年人中风死亡率和住院率的影响.
- 检查高度的影响在不同种族和种族群体之间如何变化.
- 评估高度对吸烟和药物使用等其他风险因素的影响.
主要方法:
- 利用来自3,141个美国县 (2018-2020) 的县级数据,以高度,中风死亡率/住院,药物使用,吸烟和社会人口因素为准.
- 在数据分析中采用了通用的添加模型,包括和没有共变量调整.
- 分析了按种族/种族分层的数据,以确定差异效应.
主要成果:
- 未经调整的模型表明,高度对黑人和白人人口中风死亡率有显著的负面影响.
- 在同变量调整后,高度对白人人口中风死亡率产生保护作用.
- 高度对西班牙裔和亚洲太平洋人口的心血管疾病死亡率产生不利影响,而对黑人人口而言,这种影响是无关紧要的.
结论:
- 环境因素,包括高度,导致心血管疾病和中风死亡率的种族差异.
- 高 altitude对中风结果的影响在规模上与吸烟,药物使用和健康的社会决定因素等因素相比较.
- 这些发现突出了环境,种族和心血管健康结果之间的复杂相互作用.
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