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Updated: Jan 18, 2026

Advances in Human Induced Pluripotent Stem Cell-Derived Chimeric Antigen Receptor-Expressing Natural Killer Cells
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基于IRES的RNA表达共刺激分子:癌症免疫治疗的有希望的候选者

Yun Ji Kim1, Ji Young Bang1, Hye-Won Yu1

  • 1Department of Microbiology, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea.

Molecular therapy. Nucleic acids
|January 16, 2026
PubMed
概括

这项研究引入了新的单链RNAs (ssRNAs),它们表达共刺激分子以促进T细胞对抗癌症的反应. 这些ssRNAs有效地抑制了瘤生长,并在临床前模型中诱导了回归.

关键词:
4-1BBL 4-1BBL 是一个字母.在ICOSL中,ICOSL是一个非常重要的组织.这里是IRES IRES.MT:寡核酸:治疗方法和应用.在OX40L中.T细胞的反应.

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