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维生素D缺乏作为突然神经感官听力损失的发病和复发的危险因素:一项前性队列研究与年龄特定分析
Qi Hui1, Tu Xiang1, Xiong Qinglan1
1Department of Otolaryngology, The Seventh Afffliated Hospital Sun Yat-Sen University Shenzhen China.
Food science & nutrition
|January 16, 2026
概括
维生素D缺乏与突然感觉神经听力损失 (SSNHL) 的发生和复发有关,特别是在30岁以下的人群中. 然而,诊断后短期补充剂并没有改善听力恢复.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 突然感觉神经听力损失 (SSNHL) 的复发和特定年龄的风险尚未得到充分了解.
- 维生素D (Vit D) 缺乏和SSNHL之间的联系需要进一步调查.
研究的目的:
- 调查维生素D缺乏是否会增加SSNHL发病和复发的风险.
- 检查维生素D水平和SSNHL之间的特定年龄关联.
- 评估维生素D补充剂对SSNHL患者听力恢复的疗效.
主要方法:
- 一项前性队列研究,涉及80名SSNHL患者和60名对照.
- 在基线测量血清25(OH) D水平.
- 对缺乏/不足维生素D的患者进行3个月维生素D补充的随机单盲试验.
主要成果:
- 在SSNHL患者中,维生素D缺乏的发生率明显高 (38.8%),高于对照组 (10.0%).
- 与首次出现的患者相比,复发性SSNHL患者的维生素D水平较低.
- 在30岁以下的患者中,维生素D缺乏率最高 (60.0%).
- 维生素D补充剂并没有显著改善听力恢复率或减轻症状.
结论:
- 维生素D缺乏是SSNHL发病和复发的重要,可修改的风险因素,特别是在年轻人中.
- 长期维持足够的维生素D水平对于降低SSNHL风险至关重要.
- 诊断后的急性维生素D干预不有效改善SSNHL的临床结果.
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