由于Trichoderma longibrachiatum引起的菌性牙感染在血造干细胞移植接受者中:病例报告
Eduardo Aparicio-Minguijón1, Nieves López-Muñoz2, Pilar Martínez-Sánchez2,3
1Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Centro de Actividades Ambulatorias, 6ª planta, Bloque D. Glorieta de Málaga, 11., Madrid 28041, Spain.
Therapeutic advances in infectious disease
|January 16, 2026
概括
一个罕见的真菌感染引起的Trichoderma longibrachiatum在一个免疫力低下的患者成功治疗. 结合抗真菌疗法和手术导致了临床治疗,突出显示了潜在的新治疗方案.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 移植医学 移植医学 移植医学
背景情况:
- 特里科德玛是一种罕见的细丝状真菌,在免疫受损的个体中引起侵入性感染.
- 侵入性真菌感染对患者构成重大风险,特别是对异性干细胞移植接受者.
研究的目的:
- 报告Trichoderma longibrachiatum引起的牙和鼻死菌感染病例.
- 评估这种罕见的真菌感染的治疗结果和治疗策略.
主要方法:
- 患者经历了激烈的手术脱bridement.
- 组合抗真菌疗法包括安福特素B,沃里康纳和卡斯波丁.
- 卡斯波丁后来被转换为雷扎丁,用于巩固治疗.
主要成果:
- 患者在结合治疗方法后实现了临床治愈.
- 雷扎金被用作巩固疗法,表明其在管理有限的治疗选择真菌感染方面的潜在作用.
结论:
- 侵入性Trichoderma longibrachiatum感染可能发生在免疫功能低下的患者中,例如干细胞移植接受者.
- 涉及手术干预和联合抗真菌治疗的多学科方法,可能包括rezafungin,可以导致成功的临床结果.
- 需要进一步的研究来确定雷扎金在治疗Trichoderma spp.中的有效性. 感染. 感染.
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