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Updated: Jan 18, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
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In Vitro Analysis of E3 Ubiquitin Ligase Function

Published on: May 14, 2021

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指定目标导向的微RNA降解的E3泛胺酶机制

Jakob Farnung, Elena Slobodyanyuk, Peter Y Wang

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    目标导向的微RNA降解 (TDMD) 涉及ZSWIM8与AGO-miRNA触发复合体的结合. 这种相互作用导致AGO多基化和降解,揭示了微RNAs的新型调节机制.

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