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Updated: Jan 18, 2026

Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites
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Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites

Published on: June 2, 2023

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P-Rex2表现出独特的结构特征和监管机制,与密切相关的RhoGEF P-Rex1有所区别

Lauren K Anderson, Rohan Marde, Grace Muma

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    研究人员探索了P-Rex2的结构和调节,这是一种与癌症有关的RhoGEF. 他们发现P-Rex2具有独特的自抑制机制,与P-Rex1不同,为其分子调节提供了新的见解.

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