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Updated: Jan 18, 2026

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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MYST乙转移酶是SETBP1-突变白血病中可向的治疗漏洞

Hanqian L Carlson, Thai T Nguyen, Samantha Tauchmann

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    在SET结合蛋白1 (SETBP1) 突变驱动高风险的骨髓瘤恶性瘤. 用抑制剂向MYST乙转移酶有效控制了临床前模型中的SETBP1-突变白血病,提供了一个有前途的新疗法.

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