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Updated: Jan 18, 2026

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time
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Published on: May 30, 2021

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硫化物工程揭示了人类α-synuclein的意想不到的支持和反聚合对应物

Aslam Uddin, Eugene Serebryany

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    双硫化物交叉链可以引导内在无序的蛋白质,如α-synuclein,进入特定的粉样蛋白结构. 工程交叉链接影响了α-synuclein聚合,揭示了新的多态和抗聚合效应.

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