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Updated: Jan 18, 2026

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
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Published on: December 18, 2019

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过度活跃的BMP和机械信号改造染色体,以驱动FOP中的异常骨质生成

Ellen Y Zhang, Douglas W Roberts, Sang Hyun Lee

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    纤维发育不良骨渐进症 (FOP) 是一种罕见的遗传性疾病. ACVR1 (R206H) 突变通过改变染色质状态,导致异常的骨生长,这些状态在向疗法下是可逆的.

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