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Updated: Jan 18, 2026

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在CASP8附近的染色体带2q33.1上的多种癌症风险位的功能性特征

Hyunkyung Kong, Jiyeon Choi, Tongwu Zhang

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    研究人员确定了2q33.1位点的功能变异,通过调节基因表达来影响癌症风险. 变体rs3769823以细胞类型特定的方式影响CASP8和FLACC1表达,由转录因子E4F1和IRF2.2调解.

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