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Updated: Jan 18, 2026

Evaluation of Substrate Ubiquitylation by E3 Ubiquitin-ligase in Mammalian Cell Lysates
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在C.I.C.中, elegans E3 泛素酶 EBAX-1 通过针对性微RNA 降解促进非亡的链接细胞类型死亡

Lauren B Horowitz, Olya Yarychkivska, Yun Lu

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    在C. elegans中,EBAX-1/ZSWIM8通过降解微RNA (miRNA) 来促进编程细胞死亡. 这一称为目标定向miRNA降解 (TDMD) 的过程,对于非亡发育细胞死亡至关重要.

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