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相关概念视频

Calorimetry01:19

Calorimetry

4.3K
When objects at different temperatures are placed in contact with each other but isolated from everything else, they attain thermal equilibrium. A container that prevents heat transfer in or out is called a calorimeter, and the use of a calorimeter to make measurements is called calorimetry. Generally, these measurements involve heat or specific heat capacity. The term "calorimetry problem" is used for any problem where the specified objects are thermally isolated from their...
4.3K
Constant Volume Calorimetry02:41

Constant Volume Calorimetry

30.5K
Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...
30.5K
Constant Pressure Calorimetry03:02

Constant Pressure Calorimetry

97.2K
Calorimetry is a technique used to measure the amount of heat involved in a chemical or physical process or to measure the heat transferred to or from a substance. The heat is exchanged with a calibrated and insulated device called the calorimeter. Calorimetry experiments are based on the assumption that there is no heat exchange between the insulated calorimeter and the external environment. The well-insulated calorimeters prevent the transfer of heat between the calorimeter and its external...
97.2K

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相关实验视频

Updated: Jan 18, 2026

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

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使用高度敏感的同热微热度计量量化脂肪组织热生成.

Pauke C Schots, Devesh Kesharwani, Chad C Doucette

    bioRxiv : the preprint server for biology
    |January 16, 2026
    PubMed
    概括

    这项研究优化了异热微热度计,用于测量脂肪组织热生成. 它为实验设计和组织处理提供了实际指导,以确保准确的热量生产测量.

    科学领域:

    • 代谢生理学 代谢生理学
    • 生物物理学的生物物理.

    背景情况:

    • 同热微热度计 (IMC) 直接测量热量产生,这对于理解热生成至关重要.
    • 脂肪组织研究的最佳IMC参数仍然未定义,限制了其应用.

    研究的目的:

    • 建立和验证实验条件来量化脂肪组织的热生成,使用高通量IMC.
    • 为组织处理,试验设计和数据解释提供实用指南.

    主要方法:

    • 使用了CalScreener高吞吐量IMC平台.
    • 在脂肪细胞有机体,分离的脂肪细胞和脂肪组织扩展物中评估了热生成.
    • 研究了组织处理和储存对热生成能力的影响.

    主要成果:

    • 器官体中的热量输出以尺寸和数量进行缩放,以提高测量的一致性.
    • 新鲜分离的脂肪细胞和完整的扩散体显示出强大的,仓库特异性的热生成.
    • 完整的脂肪组织在营养介质中保持了ex vivo发热能力6小时.
    • 冷藏条件,虽然保持了线粒体的完整性,但抑制了基底热量产生.

    结论:

    • 通过IMC通过脂肪组织热生成测量建立了优化的参数.

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    Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

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  • 证明了使用ex vivo脂肪组织对大型队列进行批量分析的可行性.
  • 强调了适当的组织处理和储存对于准确的热原性评估的重要性.