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Cameron D Ekanayake, Syed A Husain, Miko E Yu

medRxiv : the preprint server for health sciences

|January 16, 2026

概括

废弃脏的分发异序 (AOOS) 文档很少见,并且不一致. 这阻碍了对AOOS对移植效益的影响的准确评估,并需要为未来的途径评估提供更好的报告.

科学领域:

移植科学移植科学
器官采购器官采购
医疗健康数据分析

背景情况:

无序分配 (AOOS) 促进了器官采购组织 (OPO) 快速安置脏,绕过了标准匹配.
准确评估AOOS对器官效用的影响需要对所有尝试进行记录,包括那些没有导致移植的尝试.
目前在丢弃的脏中捕获AOOS的数据可能不足以进行全面分析.

研究的目的:

评估废弃脏中AOOS文档的频率和一致性.
在报告AOOS事件时识别潜在的数据采集缺陷.
突出需要改进AOOS报告,以评估加速分配途径.

主要方法:

移植接收者的利用科学注册表 (SRTR) 潜在的移植接收者 (PTR) 提供数据从2021-2024.
确定了至少一个被丢弃的脏的匹配运行.
根据卫生资源和服务管理局 (HRSA) 的指导方针定义的AOOS和按恢复/处置模式分层的数据,重点是2024年.

主要成果:

在2024年,只有4.3%的丢弃脏的比赛中显示了AOOS文件的证据.
在OPO中,AOOS编码的丢弃量差异很大,从0.0%到17.1% (中位数3.9%).
对丢弃脏的AOOS的文档在OPO中不常见且不一致.

结论:

在记录AOOS对丢弃脏的努力方面存在重大数据捕获缺陷.
目前的报告实践阻碍了对AOOS有效性的准确评估.
加强和一致的AOOS报告对于成功实施和评估未来的加速器官分配策略至关重要.

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